Hodgkin lymphoma (also known as Hodgkin's disease) is the name of its discoverer, Thomas Hodgkin. This disease is characterized by the presence of Reed-Sternberg cells in the body. This type of cell can be seen in the histopathological study and are usually found in malignant B cells.
These malignant B-cells grow in number, eventually causing a tumor in a lymph node or lymphoid tissue, such as bone marrow or spleen. Because of this tumor, the affected tissue loses its function, leading to stop the deterioration of the body. This disease is characterized by metastasis is ordered. If the cancer started in the lymph nodes in the neck, lymph nodes are affected, one by one, the cancer was seen in lymph nodes near the collarbone, then in the armpits, and so one.
Peaks of Hodgkin lymphoma occurs mainly in males than females, aged between 15-13 years of age above 50. What is also striking in this condition is that in the microscopic studies, more than normal cells found in lymph nodes compared with malignant cells. The cause of this disease is still unknown, however it appears that if one twin has it, the other is also at risk for Hodgkin lymphoma.
Most Reed-Sternberg cells were also observed to be infected with Epstein-Barr virus, the infectious agent of mononucleosis. Exposure to Agent Orange and the prolonged use of human growth hormone can also be explained as a factor in obtaining Hodgkin's lymphoma. Conditions that compromise the immune system such as HIV or AIDS also predispose to this disease.
Patients with non-Hodgkin's lymphoma usually have these classic signs and symptoms:
Drenching night sweats.
Sudden and unexplained weight loss
Lymph nodes are characterized as rubber and pain located in the neck, underarms and groin
Feeling tired easily
Unexplained fever that goes on and off
The itching is not related to any skin condition
When detected early, Hodgkin lymphoma shows high survival rate, making it a curable forms of cancer known to man. With proper management and treatment of Hodgkin lymphoma is still very curable, even in the later stage.
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